Chemical compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

514182, C07D40110, C07D41710, C07D41310, A61K 3150

Patent

active

050666533

ABSTRACT:
Phosphodiesterase (type III) inhibitors having the formula: ##STR1## wherein R.sup.4 is hydrogen and A is a dihydro-1,2,4-triazin-3-one group or a dihydro-1,2,4-triazin-6-one group which are useful in stimulating cardiac activity and in treating congestive heart failure and bronchoconstriction, pharmaceutical compositions including these inhibitors, and methods of using these compounds to produce phosphodiesterase (type III) inhibition in mammals.

REFERENCES:
patent: 4902795 (1990-02-01), Schriewer

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