Chemical compounds

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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Details

2603972, 2603975, A61K 3156

Patent

active

044709811

ABSTRACT:
The invention provides a compound of formula I ##STR1## where R.sup.1 represents hydrogen, lower alkanoyl or aryol, or tri-lower alkyl silyl, or a group R.sup.3 --O--CO-- (where R.sup.3 represents lower alkyl); R.sup.2 represents hydrogen, hydroxyl or fluorine and X represents --S--, --SO--, --SO.sub.2 --, --O--or --NR.sup.4 -- (where R.sup.4 represents hydrogen, lower alkyl or lower alkanoyl); the compounds are useful in the prophylaxis or management of cardiovascular disease through the regulation of serum cholesterol and a particularly useful compound is 23-thia-25-hydroxy-cholesterol.

REFERENCES:
patent: 4215045 (1980-07-01), Knapp, Jr.

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