Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-08-12
1980-03-18
Hollrah, Glennon H.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07D20506
Patent
active
041939174
ABSTRACT:
Novel semisynthetic .beta.-lactam intermediates of use in the production of cephalosporins, penicillins and related .beta.-lactam antibiotic compounds are provided. The novel compounds are prepared from .beta.-lactams obtained by cleavage of the 1,2-sulphur-carbon bond of a penicillin 1-oxide (with subsequent internal or external trapping of the sulphur atom to leave a residual substituent as the .beta.-lactam nitrogen) by removal of the said residual substituent by an oxidative cleavage reaction.
REFERENCES:
patent: 3275626 (1966-09-01), Morin et al.
Barton Derek H. R.
Elphinstone William G.
Long Alan G.
Looker Brian E.
Wilson Edward M.
Glaxo Laboratories Limited
Hollrah Glennon H.
Springer D. B.
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