Chemical compound and its use

Details Chemical compound and its use Chemical compound and its use

2005-12-15

2011-10-18

Seaman, D M (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S167000

Reexamination Certificate

active

08039629

ABSTRACT:
The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.

REFERENCES:
patent: 6069148 (2000-05-01), Schmidt et al.
patent: 6291477 (2001-09-01), Schmidt et al.
patent: 6562976 (2003-05-01), Schmidt et al.
patent: 6586613 (2003-07-01), Brandes et al.
patent: 6897317 (2005-05-01), Schmidt et al.
patent: 2002/0042515 (2002-04-01), Schmidt et al.
patent: 2005/0043341 (2005-02-01), Gielen et al.
patent: 2008/0194609 (2008-08-01), Bischoff et al.
patent: 818448 (1998-01-01), None
patent: 9915504 (1999-01-01), None
patent: 9914174 (1999-03-01), None
patent: WO-99/14215 (1999-03-01), None
patent: 03028727 (2003-04-01), None
P. A. McCarthy: “New Approaches to Atherosclerosis: An Overview,” Medicinal Research Reviews, vol. 13, No. 2, 1993, pp. 139-159.
P. J. Barter et al.: “High Density Lipoproteins and Coronary Heart Disease,” Atherosclerosis, vol. 121, 1996, pp. 1-12.
A. R. Tall: “Plasma Cholesteryl Ester Transfer Protein,” Journal of Lipid Research, vol. .34, 1993, pp. 1255-1274.
T. L. Swenson et al.: “Mechanism of Cholesteryl Ester Transfer Protein Inhibition by a Neutralizing Monoclonal Antibody and Mapping of the Monoclonal Antibody Epitope,” Teh Journal of Biological Chemistry, vol. 264, No. 24, Aug. 25, 1989, pp. 14318-14326.
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report, Circulation 2002, 106; 3143.
C. R. Sirtori: “New Targets for Lipid Lowering and Atherosclerosis Prevention,” Pharmac. Ther. vol. 67, No. 3, 1995, pp. 433-447.

Affiliated with

Also associated with

Rating

Chemical compound and its use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemical compound and its use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemical compound and its use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4282949