Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-11-13
2000-07-04
Celsa, Bennett
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 71, 422134, 422129, 430 8, 430269, 4302701, 430311, C12Q 168, G01N 3353, G03C 500, G03C 176
Patent
active
060836970
ABSTRACT:
Radiation-activated catalysts (RACs), autocatalytic reactions, and protective groups are employed to achieve a highly sensitive, high resolution, radiation directed combinatorial synthesis of pattern arrays of diverse polymers. When irradiated, RACs produce catalysts that can react with enhancers, such as those involved in autocatalytic reactions. The autocatalytic reactions produce at least one product that removes protecting groups from synthesis intermediates. This invention has a wide variety of applications and is particularly useful for the solid phase combinatorial synthesis of polymers.
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Beecher Jody E.
Goldberg Martin J.
McGall Glenn H.
Affymetrix Inc.
Celsa Bennett
Ricigliano Joseph W.
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