Chelator IDAC-2

Details Chelator IDAC-2 Chelator IDAC-2

1995-05-17

1998-09-01

Ambrose, Michael G.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to antibody or antibody fragment or immunoglobulin;...

424 153, 424 169, 530300, 530350, 534 10, 556 33, 558 17, C07F 1900, C07C33128

Patent

active

058008020

ABSTRACT:
A method for removing unbound labeling reagent from a composition comprising bound and unbound labeling reagents in which a chelator-matrix conjugate capable of binding unbound labeling reagent is contacted with a biomolecule labeling reaction mixture, by which the unbound labeling reagent is scavenged by the chelator-matrix conjugate, and then the labeled biomolecule essentially free of unbound labeling reagent is removed. Also included is a novel chelator IDAC-2, which may be used for labeling biomolecules and for scavenging in the chelator-matrix conjugate.

REFERENCES:
patent: 5244816 (1993-09-01), Subramanian et al.
patent: 5488126 (1996-01-01), Subramanian et al.

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