Chelator-functionalized nucleosides and nucleotides and methods

Details Chelator-functionalized nucleosides and nucleotides and methods Chelator-functionalized nucleosides and nucleotides and methods

1985-01-25

1989-06-06

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 28, 536 29, 536 23, C07H 2100, C07H 1900, C07H 1700, C07H 1512

Patent

active

048373125

ABSTRACT:
Nucleosides and nucleotides functionalized with a metal chelator, and methods of synthesizing such nucleosides and nucleotides are described. These compounds are useful, for example, as constituents of nucleic acid probes for diagnostic and therapeutic purposes.

REFERENCES:
patent: 4529796 (1985-07-01), Kang et al.
patent: 4665184 (1987-05-01), Dervan et al.
Bergstrom, D. E. et al., J. Amer. Chem. Soc., vol. 100, No. 26, 1978, pp. 8106-8112.
Hertzberg, R. P. et al., Biochemistry, vol. 23, No. 17, 1984, pp. 3934-3945.
Schultz, P. G. et al., Proc. Natl. Acad. Sci. USA, vol. 80, 1983, pp. 6834-6837.
Chu, B. C. F. et al., Nucleic Acids Research, vol. 11, No. 18, 1983, pp. 6513-6529.

Affiliated with

Also associated with

Rating

Chelator-functionalized nucleosides and nucleotides and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chelator-functionalized nucleosides and nucleotides and methods , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chelator-functionalized nucleosides and nucleotides and methods will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-41231