Drug – bio-affecting and body treating compositions – Topical sun or radiation screening – or tanning preparations
Patent
1992-11-09
1994-11-15
Richter, Johann
Drug, bio-affecting and body treating compositions
Topical sun or radiation screening, or tanning preparations
514461, 514473, 549473, A61K 742, A61K 3134, C07D31500
Patent
active
053646177
ABSTRACT:
The present invention involves photoprotective compositions which are useful for topical application to prevent damage to skin caused by acute or chronic exposure to ultraviolet light comprising chelating agents having the formula ##STR1## wherein --R.sup.1 and --R.sup.2 are independently selected from the group consisting of alkyl, aryl, and heteroaryl, or R.sup.1 and R.sup.2 may be covalently bonded together to form a cyclic alkyl; --M is selected from the group consisting of =0, =S, --SR.sup.4 and --OR.sup.4 (when --M is --OR.sup.4 or --SR.sup.4, there is a hydrogen bonded to the carbon to which --M is bonded); --R.sup.4 is selected from the group consisting of hydrogen, alkyl, aryl and heteroaryl; --R.sup.3 is selected from the group consisting of hydrogen, alkyl, aryl and heteroaryl; --R.sup.6 is selected from the group consisting of hydrogen alkyl, aryl and heteroaryl; and i is selected from the group consisting of one and zero. Methods for using such compositions to prevent damage to skin caused by acute or chronic exposure to ultraviolet light are al so involved.
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Bissett Donald L.
Bush Rodney D.
Chatterjee Ranjit
Graff IV Milton B.
Kilby Scalzo Catherine S.
Richter Johann
Simon Soma G.
Suter David L.
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