Chelating compounds for metal-radionuclide labeled proteins

Details Chelating compounds for metal-radionuclide labeled proteins Chelating compounds for metal-radionuclide labeled proteins

1988-03-23

1990-10-23

Maples, John S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Esters having the thiocarboxylate group, -cx-, wherein the...

560145, 424 11, C07C 6962, C07C32706

Patent

active

049653920

ABSTRACT:
Chelated radionuclide compositions are provided for conjugation to polypeptides and carbohydrates. The resulting conjugates may be used in diagnosis and therapy. Chelating compounds are disclosed.

REFERENCES:
patent: 4671958 (1987-06-01), Rodwell et al.
patent: 4741900 (1988-05-01), Alvarez et al.
patent: 4861869 (1989-08-01), Nicolotti et al.
Fritzberg et al., "Synthesis and Biological Evaluation of Technetium-99m MAG.sub.3 as a Hippuran Replacement", J. Nuc. Med., vol. 27, No. 1, Fritzberg et al. (I), Jan. 1986.
Fritzberg et al., "Synthesis and Characterization of Re and Tc Complexes of N2S2 and N3S Ligands", Sixth International Symposium on Radio-pharmaceutical Chemistry, 1986 (Fritzberg et al. II).
Nosco et al., "Characterization of the New [Tc-99m] Dynamic Renal Imaging Agent: [Tc-99m] MAG.sub.3." J. Nuc. Med., vol. 27, No. 6, Jun., 1986, p. 939, Abstract No. 256.
Verbruggen et al., "Relation Between Structure and Renal Transport of Isomeric Methylderivatives of Tc-99m Mercaptoacetyltriglycine", J. Nuc. Med., vol. 27, No. 6, Jun., 1986, p. 894, Abstract No. 76.
Taylor et al., "Preliminary Evaluation of 99m Tc Mercaptoacetyltriglycine as a Replacement for .sup.131 I OIH" Contr. Nephrol., vol. 56,5 (Taylor et al. II).
Taylor et al., "Comparison of Tc-99m Mercaptoacetyltriglycine (MAG.sub.3) and OIH in Normal Subjects and Patients", J. Nuc. Med., vol. 27, No. 6, Jun., 1986, p. 962, Abstract No. 351 (Taylor et al. I).
Taylor et al., "Preliminary Evaluation of Technetium-99m Mercaptoacetyltriglycine (MAG.sub.3) as a Replacement for Iodine-131OIH." J. Nuc. Med., vol. 27, No. 4, Apr. 1986, Taylor et al. III.
Muller-Suur et al., "Clearance and Renal Extraction of a New Renal Scanning Agent: Technetium-99m MAG.sub.3 in Comparison to Hippurate (OIH) and EDTA. C." J. Nuc. Med., vol. 26, No. 4, Apr. 1986.
deJong et al., "Results of ERBF and ERPF Measurements in Healthy Dogs with Two New Radiopharmaceutical Principles." J. Nuc. Med., vol. 27, No. 4, Apr. 1986.
Bubeck et al., "Clinical Comparison of I-131 o-Iodohippurate with Tc-99m CO.sub.2 -DADS-A and Tc-99m MAG.sub.3 by Simultaneous Double Tracer Measurement." Alsfelder Strasse 10.6100 Darmstadt Nuc Compact 17 (1986) 135-138.
T. W. Greene, "Protective Groups in Organic Synthesis", John Wiley and Sons, New York, New York, pp. 204-209 and 216-217.

Affiliated with

Also associated with

Rating

Chelating compounds for metal-radionuclide labeled proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chelating compounds for metal-radionuclide labeled proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chelating compounds for metal-radionuclide labeled proteins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-767970