Chelating agents for forming complexes with radioactive isotopes

Details Chelating agents for forming complexes with radioactive isotopes Chelating agents for forming complexes with radioactive isotopes

1990-08-22

1994-04-12

Stoll, Robert L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to antibody or antibody fragment or immunoglobulin;...

424 165, 534 10, 534 14, 5303915, 548518, 548546, 548561, 564367, 564370, 564336, 564337, 564310, 564313, 564464, 549 59, 549 74, 549 75, A61K 4902, C07C21127, C07C21125

Patent

active

053023706

ABSTRACT:
The invention relates to compounds having the general formula I ##STR1## where A if required can contain a functional and/or activated group C for coupling to selectively concentrating compounds or can contain a selectively concentrating compound coupled via the group C. B and B' are functional groups for coordinate bonding of groups carrying metal ions. The novel compounds are for forming complexes with radioactive metal ions, more particularly rhenium and technetium isotopes, and are used in medical diagnosis and therapy.

REFERENCES:
patent: 2624759 (1953-01-01), Bersworth
patent: 2876236 (1959-03-01), Szabo et al.
patent: 3933913 (1976-01-01), Colella et al.
patent: 4152345 (1979-05-01), Gaudette et al.
patent: 4758682 (1988-07-01), Collins et al.
patent: 5071965 (1991-12-01), Dunn et al.
patent: 5101041 (1992-03-01), Troutner et al.
patent: 5104638 (1992-04-01), Nosco

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