Chelating agents and method

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

562565, 562556, 562564, 562448, 548496, 548450, 534573, 534558, C07C10126

Patent

active

046224203

ABSTRACT:
A simple method for making EDTA, ED3A or DTPA analogs from amide derivatives of alpha amino acids is disclosed. These EDTA, ED3A or DTPA analogs are useful chelating agents, and preferably are useful as bifunctional chelating agents which may be attached to biological molecules and which form physiologically stable chelates with a variety of metal ions.

REFERENCES:
patent: 2893916 (1959-07-01), Rubin
patent: 3062719 (1962-11-01), Rubin et al.
patent: 3780100 (1973-12-01), Scanlon et al.
patent: 3994966 (1976-11-01), Sundberg et al.
patent: 4043998 (1977-08-01), Meares et al.
patent: 4352751 (1982-10-01), Wieder et al.
patent: 4432907 (1984-02-01), Wieder et al.
Journal of Radioanalytical Chemistry, vol. 53, No. 1-2 (1979) pp. 327-336.
Analytical Biochemistry 100, pp. 152-159 (1979).
JACS, 92:6 (1970), pp. 1637-1646.
Chemistry of Amino Acids, Greenstein, pp. 927-933.
Tetahedron, vol. 24, pp. 1145-1162 (1968).
JACS, vol. 81, pp. 2955-2957 (1959).
Chem. Pharm. Bull., vol. 13 (1), pp. 88-93 (1965).
J. Med. Chem., 17, 1304-1307 (1974).
Proc. Nat'l. Acad. Sci., U.S.A., 73, pp. 3803, 3806 (1976).
ACS/CSJ Chemical Congress, Abstracts of Papers, Apr. 1-6, 1979, No. 53.
J. Med. Chem., vol. 19, pp. 962-964 (1976).
J. Pharm. Sci., vol. 64, pp. 704-706 (1975).
Biochem. & Biophys. Res. Com., vol. 22, pp. 581-585 (1977).
Bull. Chem. Soc. Japan, vol. 40, pp. 2326-2332 (1967).
J. Org. Chem., vol. 36, No. 17, pp. 2548-2550 (1971).
Bull. Chem. Soc. Japan, 45, M. Saburi et al., pp. 806-811, 1086-1093 (1972).
Chelating Agents and Metal Chelates, (ed. Dwyer et al.), Academic Press (1964), pp. 283-289, 328-331.
J. Org. Chem., vol. 41, No. 7, Roeske, et al., pp. 1260-1261 (1976).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Chelating agents and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chelating agents and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chelating agents and method will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-378151

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.