Chelated complexes of paramagnetic metals with low toxicity

Details Chelated complexes of paramagnetic metals with low toxicity Chelated complexes of paramagnetic metals with low toxicity

1998-04-16

2000-11-21

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Testing efficacy or toxicity of a compound or composition

540465, 540474, 534 16, 534 10, 534 14, 534 15, A61B 5055, C07D22500, C07F 500

Patent

active

061498904

ABSTRACT:
Compounds of formulae (I) and (II) ##STR1## wherein the R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 groups have the meanings defined in the disclosure, are useful chelants for metal ions. The complexes of compounds (I) and (II) with paramagnetic ions are useful as contrast agents for M.R.I. imaging.

REFERENCES:
patent: 5747000 (1998-05-01), Platzek et al.

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