Chelate derivatives as protectors against tissue injury

Details Chelate derivatives as protectors against tissue injury Chelate derivatives as protectors against tissue injury

1997-04-21

2000-02-01

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514252, 514255, 514551, 514563, 544357, 544385, 560169, 562564, A61K 31225

Patent

active

060203730

ABSTRACT:
Derivatives useful in the protection of living organisms against damage due to free radical reactions derived from methoxypolyethylene glycols (MPEG), which are modified by chemically attaching chelating groups in an amide or amine linkage to the nonmethyl end of the polymer. Such chelating groups include ethylene-diamine tetraacetic acid (EDTA), diethylene triamine pentaacetic acid (DTPA), and ethylene glycol aminoethyl ether tetraacetic acid (EGTA), and pharmacologically acceptable salts or esters thereof.

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