Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Silicon containing doai
Patent
1993-02-25
1994-10-25
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Silicon containing doai
540 3, 540 4, 514176, 514183, A61K 3140, C07J 7300
Patent
active
053589408
ABSTRACT:
Naphthalocyanine-chelate complexes of formula I ##STR1## are described which contain as central atom M aluminum, gallium, indium, fin, ruthenium or preferably germanium and in which the remaining symbols are as defined in claim 1. The complexes can be used inter alia in the photodynamic chemotherapy of tumors.
REFERENCES:
Joyner et al. JACS vol. 82, 1960 pp. 5790-5792.
Freedman, et al. J. Org. Chem. 1991 56 670-672.
Joyner et al. Inorganic Chem. 1962, 1, pp. 236-238.
Boksanyi, et al. Helv. Chim. Acta, 59(3), 1976 pp. 717-727.
Davis, J. Chem. Soc. 1962 pp. 178-181.
Pedersen, JACS vol. 89, 1967 pp. 7017-7036.
Borisenkova et al Chemical Abstracts, vol. 91. 1979, Abstract 9929w.
Nevin et al Inorganic Chemistry 1987 26 891-899.
Keppeler et al. Chem. Ber. 119 3363-3381, 1986.
Manivannan et al. Chemical Abstracts, vol. 110, 1989 Abstract 143348v.
Janda et al. Chemical Abstracts, vol. 111, 1989 Abstract 66590j.
Miyazaki et al Chemical Abstracts vol. 111, 1989 Abstract 144225k.
Mooney, et al. JACS 97(11), 1975, pp. 3033-3038.
Wheeler et al JACS vol. 106, 1984 7404-7410.
Rihter, et al. Chem. Abs. vol. 117, 1992 Abstract 187382a.
Hoh et al., Chemical Abstracts, vol. 111, 1989 Abstract 2244430s.
Shatskaya, et al. Chemical Abstracts vol. 108, 1988 Abstract 57881r.
Rihter et al: "Synthesis and Photoproperties of Diamagnetic Octabutoxyphthalocyanines with Deep Red Optical Absorbance" J. Am. Chem. Soc. BD 112, (1990) pp. 8064-8070.
Cuomo et al: Tumor-Localizing and -Photosensitizing Properties of Liposome-Delivered Germanium (IV) Octabutoxyphthalacyanine--Chemical Abstracts vol. 116, (1992) Columbus Ohio 37092w. p. 351.
Esposito J et al. "Infrared and Nuclear Magnetic Resonance Studies of Some Germanium Phthalocyanines and Hemiporphyrazines" Inorganic Chemistry BD 6, Nr 6, (1967 pp. 1116-1120.
Era et al "Optical Recording Medium with Phthalocyanine Recording Film" Chemical Abstracts vol. 112: (1990) Columbus Ohio 108644h p. 680.
Kobayashi et al "Phthalocyanine Compounds and OPtical Information Recording Media Using Them and Their Manufacture" Chemical Abstract vol. 114-(1991) Columbus Ohio. 111977r p. 672.
Perry et al "Excited State Absorption and Optical Limiting in Solutions of Metallophthalocanines" Chemical Abstracts vol. 115 (1991) Columbus Ohio-243124r p. 750.
Semenov S. G. et al "Quantum Chemical Calculation of the Electronic Absorption Spectra and Ionization Potentials of Silicon and Germanium PHthalocyanine [PcSi(OSiMe.sub.3).sub.2 ] and PcGe(OSiMe.sub.3).sub.2 ] and Silicon Tetrazporphyrin [TAPSI(OSiMe.sub.3 (.sub.2 ]" Chemical Abstracts; vol. 11 (1989)--Columbus Ohio 143681 p. 572.
Cuomo et al, "Tumour-Localising and -Photosensitizing Properties of Liposome-Delivered GE(IV)-Octabutoxyphthalocyanine" Br. J. Cancer 64 (1991) 93-95.
Sounik et al "Synthesis and Characterization of Naphthalocyanines and Phthalocyanines of Use in Sensitizer Studies" SPIE 1203-(1990) 224-229.
Richter et al "Three New Phthalocyanines with Potential for PDT Studies" SPIE 1645 (Jan. 1992) 251-258.
Chemical Abstract 116-121677u (1992) p. 691 Miyazaki "Write-once-type Optical Disk Containing Phtalocyanine Dye" corresponding to JP 03,281,388.
Chemical Abstract 113-142433u (1990) p. 709-710 Sakamoto et al "Optical Recording Medium Containing Phthalocyanine Derivative" corresponding to JP 01,297,293.
Cuomo et al "Liposome-Delivered Si(TV)-Naphthalocyanine as a Photodynamic Sensitiser for Experimental Tumors: Pharmacokinetic and Phototherapeutic Studies" Br. J. Cancer 62 (1990) 966-970.
Derwent Abstract Nr 89-288563/40. Toyo Ink Mfg KK.
Baumann Marcus
Capraro Hans G.
Ciba-Geigy Corporation
Fishman Irving M.
Kaiser Karen G.
Shah Mukund J.
Sripada Pavanaram K.
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