Chartreusin derivatives and salts thereof

Details Chartreusin derivatives and salts thereof Chartreusin derivatives and salts thereof

1985-04-23

1988-07-26

Brown, J. R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 172, 536 181, C07H 1704

Patent

active

047601361

ABSTRACT:
This invention relates to a novel chartreusin derivative of the general formula (I): ##STR1## and a salt thereof. This chartreusin derivative and a salt thereof have an excellent antitumor activity, which is exhibited even when the site of cancer inoculation and the site of drug administration are different. This invention further relates to a antitumorous composition containing the above-mentioned compound as active ingredient. This invention furthermore relates to a process for producing the above-mentioned chartreusin derivative or salt thereof.

REFERENCES:
patent: 4518589 (1985-05-01), Konishi et al.
patent: 4521240 (1985-06-01), Loh
The Merck Index, 1976, No. 1997, p. 256.
Cancer Research 37, pp. 1666-1672, Jun. 1977-J. Patrick McGovren et al.
Eisenhuth et al.; English translation.
Johnson et al., Cancer Treatment Reviews (1975) vol. 2, pp. 1-31.

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