Charge tags and the separation of nucleic acid molecules

Details Charge tags and the separation of nucleic acid molecules Charge tags and the separation of nucleic acid molecules

2008-06-10

2008-06-10

Riley, Jezia (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C536S023100, C536S024300, C536S024330, C536S026600

Reexamination Certificate

active

07384746

ABSTRACT:
The present invention relates to novel phosphoramidites, including positive and neutrally charged compounds. The present invention also provides charge tags for attachment to materials including solid supports and nucleic acids, wherein the charge tags increase or decrease the net charge of the material. The present invention further provides methods for separating and characterizing molecules based on the charge differentials between modified and unmodified materials.

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