Characterization of replication competent human immunodeficiency

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits

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4352351, 536 235, 930221, 935 1, 935 6, 935 9, 935 11, 935 19, C12N 1549, C12N 702, C12N 704, C07H 2104

Patent

active

052234231

ABSTRACT:
A complete genomic clone of HIV-2 designated HIV-2.sub.SBL/ISY was cloned from DNA of the neoplastic human cell line HUT78 infected with the HIV-2.sub.SBL6669 viral isolate. The clone was sequenced and the sequence compared with those of known HIV-2 isolates. The invention is advantageous for it provides an animal model for the study of HIV infection in man.

REFERENCES:
Guyader, M. et al (1987) Nature 326, 662-669.
Albert, J. et al (1987) AIDS Res. and Human Retroviruses 3, 3-10.
Franchini, G. et al (1987) AIDS Res. and Human Retroviruses 3, 11-17.
Nicol, I. et al (1989) Intervirology 30, 258-267.

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