Optics: measuring and testing – By dispersed light spectroscopy – With sample excitation
Reexamination Certificate
2006-05-30
2006-05-30
Lee, Hwa (Andrew) (Department: 2877)
Optics: measuring and testing
By dispersed light spectroscopy
With sample excitation
C250S459100
Reexamination Certificate
active
07054002
ABSTRACT:
A system (20) of the present invention includes light source instrumentation (30) to selectively illuminate a light scattering medium including a luminophore and detection instrumentation (50) to detect multiply scattered light output from the medium in response to illumination by the light source instrumentation (30). A processor (70) is operatively coupled to the detection instrumentation (50) to determine a first optical characterization of the medium from a first multiply scattered light output of a first illumination light wavelength and a second optical characterization of the medium from a second multiply scattered light output of a second illumination light wavelength different than the first illumination light wavelength. The processor (70) is operable to calculate lifetime of the luminophore from the first optical characterization, the second optical characterization, and a multiply scattered emission of the luminophore from the medium in response to excitation.
REFERENCES:
patent: 4245909 (1981-01-01), Loos
patent: 4541438 (1985-09-01), Parker et al.
patent: 4641969 (1987-02-01), Lundberg et al.
patent: 4781460 (1988-11-01), Bott
patent: 4871251 (1989-10-01), Preikschat et al.
patent: 4890920 (1990-01-01), Niziolek et al.
patent: 5022757 (1991-06-01), Modell
patent: 5119815 (1992-06-01), Chance
patent: 5142372 (1992-08-01), Alfano et al.
patent: 5164787 (1992-11-01), Tgushi et al.
patent: 5190729 (1993-03-01), Hauenstein et al.
patent: 5208651 (1993-05-01), Buican
patent: 5213105 (1993-05-01), Gratton et al.
patent: 5229839 (1993-07-01), Hayashi et al.
patent: 5340991 (1994-08-01), Fransen et al.
patent: 5353799 (1994-10-01), Chance
patent: 5413098 (1995-05-01), Benaron
patent: 5416580 (1995-05-01), Trainer
patent: 5421337 (1995-06-01), Richards-Kortum et al.
patent: 5421339 (1995-06-01), Ramanujam et al.
patent: 5424843 (1995-06-01), Tromberg et al.
patent: 5438408 (1995-08-01), Weichert et al.
patent: 5441054 (1995-08-01), Tsuchiva
patent: 5452723 (1995-09-01), Wu et al.
patent: 5455675 (1995-10-01), Witt et al.
patent: 5485530 (1996-01-01), Lakowicz et al.
patent: 5502561 (1996-03-01), Hutchins et al.
patent: 5504337 (1996-04-01), Lakowicz et al.
patent: 5507287 (1996-04-01), Palcic et al.
patent: 5579773 (1996-12-01), Vo-Dinh et al.
patent: 5582168 (1996-12-01), Samuels et al.
patent: 5590660 (1997-01-01), MacAulay
patent: 5619324 (1997-04-01), Harvill et al.
patent: 5624847 (1997-04-01), Lakowicz et al.
patent: 5628310 (1997-05-01), Rao et al.
patent: 5647368 (1997-07-01), Zeng et al.
patent: 5692504 (1997-12-01), Essenpreis et al.
patent: 5699798 (1997-12-01), Hochman et al.
patent: 5736410 (1998-04-01), Zarling et al.
patent: 5759767 (1998-06-01), Lakowicz et al.
patent: 5792049 (1998-08-01), Eppstein et al.
patent: 5818583 (1998-10-01), Sevick-Muraca et al.
patent: 5860421 (1999-01-01), Eppstein et al.
patent: 5865754 (1999-02-01), Sevick-Muraca et al.
patent: 5891656 (1999-04-01), Zarling et al.
patent: 5917190 (1999-06-01), Yodh et al.
patent: 5949077 (1999-09-01), Alfano et al.
patent: 6216540 (2001-04-01), Nelson et al.
patent: 6271522 (2001-08-01), Lindermeir et al.
patent: 6480276 (2002-11-01), Jiang
patent: 2002/0072677 (2002-06-01), Sevick-Muraca et al.
patent: 2003/0117622 (2003-06-01), Sevick-Muraca et al.
patent: 2005/0073681 (2005-04-01), Sevick-Muraca et al.
patent: 0 959 341 (1999-11-01), None
patent: 2311366 (1996-03-01), None
patent: 2-268256 (1990-01-01), None
patent: WO 95/12132 (1995-05-01), None
patent: WO 99/49312 (1999-03-01), None
patent: WO 00/22414 (1999-10-01), None
patent: WO 02/41760 (2000-05-01), None
patent: WO 01/22063 (2000-09-01), None
Mayer, Ralf H., et al., “Measurement of the Fluorescence Lifetime in Scattering Media by Frequency-Domain Photon Migration”, Applied Optics, vol. 38, No. 22, Aug. 1, 1999, pp. 4930-4938.
Cerussi, Albert E., et al., “Experimental Verification of a Theory for the Time-Resolved Fluorescence Spectroscopy of Thick Tissues”, Applied Optics, vol. 36, No. 1, Jan. 1, 1997, pp. 116-124.
Hutchinson, Christina L., et al., “Fluorescence-Lifetime Determination in Tissues or Other Scattering Media from Measurement of Excitation and Emission Kinetics”, Applied Optics, vol. 35, No. 13, May 1, 1996, pp. 2325-2332.
M.A. O'Leary, E.A. Boas, X.D. Li, B. Chance, and A.G. Yodh., “Fluorescence Lifetime Imaging in Turbid Media,” Optics Letters, vol. 21, No. 2, pp. 158-160, Jan. 15, 1966.
Sevick-Muraca, et al.; “Method and System for Detecting Sentinel Lymph Nodes;” U.S. Appl. No. 10/618,194; 28 pgs, Jul. 11, 2003.
Sevick-Muraca, et al.; “Method for Characterizing Particles in Suspension from Frequency Domain Phton Migration Measurements” U.S. Appl. No. 10/115,271; 59 pgs, Apr. 3, 2002.
Dilip Paithankar, Jeff Kao, and Eva Sevick-Muraca,Particle Size Distribution Estimation Via Solution of the Inverse Problem of Multi-Wavelength Scattering Coefficient Measurements, Chem. Eng. Prog., Aug. 1995.
Sevick-Muraca, et al.;Method for Characterizing Particles in Suspension from Frequency Domain Photon Migration Measurements; U.S. Appl. No. 11/204,844; 59 pgs, Aug. 16, 2005.
Robert J. Farrell and Yen-Cheng Tsai,Nonlinear Controller for Batch Crystallization: Development and Experimental Demonstration, AIChE Journal, vol. 41, No. 10, at 2318, Oct. 1995.
Huabei Jiang, Keith D. Paulsen, Ulf L. Osterberg, Brian W. Pogue and Michael S. Patterson,Optical Image Reconstruction Using Frequency-Domain Data: Simulations and Experiments, Journal of the Optical Society of America, at 253, Sep. 1995.
Alwin Kienle, Lothar Lilge, Michel S. Patterson, Raimund Hibst, Rudolf Steiner, and Brian C. Wilson,Spatially Resolved Absolute Diffuse Reflectance Measurements for Noninvasive Determination of the Optical Scattering and Absorption Coefficients of Biological Tissue, Applied Optics, vol. 35, No. 13 at 2304, May 1996.
Pi-Huan Wang, Geoffrey S. Kent, M. Patrick McCormick, Larry W. Thomason, and Glenn K. Yue,Retrieval Analysis of Aerosol-Size Distribution with Simulated Extinction Measurements at SAGE III Wavelenghts, Applied Optics, vol. 35, No. 3 at 433, Jan. 1996.
Kusiel S. Shifrin and Ilja G. Zolotov,Spectral Attenuation and Aerosol Particle Size Distribution, Applied Optics, vol. 35, No. 12 at 2114, Apr. 1996.
Jianhong Wang and F. Ross Hallett,Spherical Particle Size Determination by Analytical Inversion of the UV-Visible-NIR Extinction Spectrum, Applied Optics, vol. 35, No. 1, at 193, Jan. 1996.
Sergei A. Vinogradov, Leu-Wei Lo, William T. Jenkins, Sydney M. Evans, Cameron Koch, and David F. Wilson,Noninvasive Imaging of the Distribution in Oxygen in Tissue in Vivo Using Near-Infrared Phosphors, Biophysical Journal, vol. 70, at 1609-1617, Apr. 1996.
Joshua B. Fishkin, Peter T.C. So, Albert E. Cerussi, Sergio Fantini, Maria Angela Franceschini, and Enrico Gratton,Frequency-Domain Method for Measuring Spectral Properties in Multiple-Scattering Media: Methemoglobin Absorption Spectrum in a Tissuelike Phantom, Applied Optics, vol. 34 No. 7, at 1143, Mar. 1995.
Heimo Schnablegger and Otto Glatter,Sizing of Colloidal Particles with Light Scattering: Corrections for Beginning Multiple Scattering, Applied Optics, vol. 34, No. 18, at 3489, Jun. 1995.
M.A. O'Leary, D.A. Boas, B. Chance, and A.G. Yodh,Experimental Images of Heterogeneous Turbid Media by Frequency-Domain Diffusing-Photon Tomography, Optics Letters, vol. 20, No. 5, at 426, Mar. 1995.
Jozef Vavra, Jozef Antalik and Marek Liska,Application of Regression Analysis in Spectroturbidity Size-Characterization Methods, Part. Syst. Charact. 12, 38-41, 1995.
Reynolds, et al., “Imaging of Spontaneous Canine Mammary Tumors Using Fluorescent Contrast Agents”, Photochemistry and Photobiology, 1999: 70(1): 87-94 (XP-001063376), Apr. 14, 1999.
Gurfinkel, et al., “Pharmocokinetcs of ICG and HPPH-car for the Detection of Normal and Tumor Tissue Using Fluorescence, Near-infrared Reflectance Imaging: A Case Study”, Photochemistry and Photobiology, 2000: 72(1): 94-102 (XP-001030699), Apr. 28, 2000.
Thom
Mayer Ralf H.
Reynolds Jeffery S.
Sevick-Muraca Eva M.
Baker & Botts L.L.P.
Lee Hwa (Andrew)
Merlino Amanda H.
The Texas A&M University System
LandOfFree
Characterization of luminescence in a scattering medium does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Characterization of luminescence in a scattering medium, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Characterization of luminescence in a scattering medium will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3610272