Channel catfish virus disease vaccine and method of preparation

Details Channel catfish virus disease vaccine and method of preparation Channel catfish virus disease vaccine and method of preparation

1979-05-18

1980-08-26

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

435235, 435237, A61K 3912

Patent

active

042195438

ABSTRACT:
The invention relates to a channel catfish virus vaccine comprising an attenuated strain or strains of channel catfish virus and a pharmaceutically acceptable diluent and a method of preparation thereof comprising the serial passage of a channel catfish virus through a plurality of tissue cell cultures until the resulting virus material is sufficiently attenuated to permit its safe administration to channel catfish. The invention also relates to a method of immunizing channel catfish from channel catfish virus disease comprising hyperosmotically infiltrating the channel catfish with the above-described vaccine followed by a the hyperosmotic infiltration thereof with a booster dose of said vaccine.

REFERENCES:
patent: 4009259 (1977-02-01), Ament et al.
Bowser, P. R., Development and Evaluation of a New Cell Line from the Channel Catfish, Ktalurus Punctatus Ph.D (1978) Diss. Abs. Intl. 39(9), Sec. B, p. 4120.
Glenn, J. S., The Immune Response of the Channel Catfish (Ictalurus Punctatus) Ph.D (1974) Diss. Abs. Intl. 35(10), Sec. B, p. 5199.
Austen, J. D., Pathogenesis of Channel Catfish Virus Disease and Characterization of the Virus Ph.D (1977) Diss. Abs. Int. 38(11), Sec. B, p. 5187.
Schachte, J. H., Studies on the Immunization of the Channel Catfish against Two Bacterial Pathogens Ph.D (1976) Diss. Abs. Int. 37(5), Sec. B, p. 2030.

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