Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1990-08-03
1992-02-18
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
562460, 562463, C07C 6976
Patent
active
050896547
ABSTRACT:
Chalcone derivatives represented by the formula ##STR1## wherein R.sup.1 is a straight chain, branched chain or cyclic alkyl group having 4 to 15 carbon atoms or an alkenyl group having 3 to 15 carbon atoms, and occurs at the 2- or 4-position, R.sup.2 is a hydrogen atom, a straight or branched chain alkyl group having 1 to 3 carbon atoms, and X is a straight or branched chain alkylene group having 1 to 3 carbon atoms, are disclosed. These compounds have anti-ulcer effect, gastric mucosal protection effect and antisecretory effect.
REFERENCES:
patent: 4085135 (1978-04-01), Kyogoku et al.
patent: 4656305 (1987-04-01), Vanstone et al.
Chemical Abstracts, vol. 99, No. 15, 10/10/83, p. 614, col. 1, No. 122052h.
Chemical Abstracts, vol. 99, No. 15, 12/83, p. 721, col. 1, No. 194622s.
Chemical Abstracts, vol. 100, No. 3, 1/16/84, p. 469, col. 2, No. 22418c.
Hatayama Katsuo
Matsunaga Tohru
Nakashima Yoshimoto
Saijo Keiko
Yokomori Sadakazu
Killos Paul J.
Taisho Pharmaceutical Co. Ltd.
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