Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ketone doai
Reexamination Certificate
2005-03-08
2008-10-07
Davis, Zinna N (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ketone doai
C514S680000, C568S325000, C568S326000
Reexamination Certificate
active
07432303
ABSTRACT:
The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good activity as angiogenesis inhibitors. The present invention also relates to the use of chalcone and its analogs as antitumor/anticancer agents and to treat a number of conditions or disease states in which angiogenesis is a factor, including angiongenic skin diseases such as psoriasis, acne, rosacea, warts, eczema, hemangiomas, lymphangiogenesis, among numerous others, as well as chronic inflammatory disease such as arthritis.
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Arbiser Jack
Bowen J. Phillip
Ehlers Tedman
Goldsmith David
Robinson Thomas Philip
Bowen J. Phillip
Coleman Henry D.
Davis Zinna N
Ehlers Tedman
James and Emory University
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