Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-03-15
2011-03-15
Kosack, Joseph R (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S001000
Reexamination Certificate
active
07906500
ABSTRACT:
Provided are chalcogenoxanthylium compounds which can effectively be used as sensitizers in photodynamic therapy, virucides in photodynamic antimicrobial chemotherapy and reversal agents of Pgp function in cancer cells. Further provided is a general method for the preparation of chalcogenoxanthylium compounds.
REFERENCES:
patent: 0 330 444 (1989-08-01), None
patent: 11-279426 (1999-10-01), None
Detty et al. “Synthesis, properties, and photodynamic properties in vitro of heavy-chalcogen analogues of tetramethylrosamine” Bioorganic & Medicinal Chemistry, Apr. 13, 2004 vol. 12, pp. 2537-2544.
Ohulchanskyy et al. “Heteroatom Substitution Induced Changes in Excited-State Photophysics and Singlet Oxygen Generation in Chalcogenoxanthylium Dyes: Effect of Sulfur and Selenium Substitutions” Journal of Physical Chemistry B May 1, 2004, vol. 108, pp. 8668-8672.
Chemical Abstracts Accession No. 1983:135090.
Detty, M. R., et al., “Synthesis, properties, and photodynamic properties in vitro of heavy-chalcogen analogues of tetramethylrosamine,” Bioorganic & Medicinal Chemistry, Apr. 13, 2004, pp. 2537-2544, vol. 12, Elsevier.
Ohulchanskyy, T. Y., et al., “Heteroatom Substitution Induced Changes in Excited-State Photophysics and Singlet Oxygen Generation in Chalcogenoxanthylium Dyes: Effect of Sulfur and Selenium Substitutions,” Journal of Physical Chemistry B, May 1, 2004, pp. 8668-8672, vol. 108, American Chemical Society.
Nealy et al; Synthesis of 3,6-Bis(dimethylamino)thio- and Selenoxanthene (1); Monsanto Research Corporation, Boston Laboratory, vol. 3, pp. 228-229, 1966.
Detty Michael R.
Donnelly David J.
Hodgson & Russ LLP
Kosack Joseph R
The Research Foundation of State University of New York
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