Chain terminators for DNA synthesis

Details Chain terminators for DNA synthesis Chain terminators for DNA synthesis

2005-02-22

2005-02-22

Crane, L. E. (Department: 1623)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091200, C544S243000, C544S264000

Reexamination Certificate

active

06858393

ABSTRACT:
The invention relates to acyclic chain terminator nucleotide analogs. More particularly, the invention relates to phosphonomethoxyethyl nucleotide analogs and detectably labeled versions thereof, especially fluorescently labeled versions thereof. The invention further relates to the use of chain terminating phosphonomethoxyethyl nucleotide analogs in methods of synthesizing a polynucleotide, labeling a polynucleotide, determining polynucleotide sequence information, and kits therefor.

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