Chain-terminated N-vinyl lactam polymers and graft-copolymers an

Details Chain-terminated N-vinyl lactam polymers and graft-copolymers an Chain-terminated N-vinyl lactam polymers and graft-copolymers an

1993-08-26

1997-05-20

Schofer, Joseph L.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Polymers from only ethylenic monomers or processes of...

526 82, 526 84, C08F12606, C08F12610, C08F 238

Patent

active

056313365

ABSTRACT:
A water-soluble polyvinyl 5-membered lactam having a molecular weight ranging from about 1000 to about 20,000 and chain-terminated with a compound selected from the group consisting of compounds of the following formulas ##STR1## wherein R and R.sup.1 are C.sub.1 to C.sub.4 alkyl or substituted alkyl; n is 0 to 20; R.sup.II is ethylene; R.sup.III is C.sub.1 to C.sub.24 alkylene or substituted alkylene; and R.sup.IV is C.sub.1 to C.sub.4 alkyl or substituted alkyl; can be prepared by polymerizing an N-vinyl 5-membered lactam in a liquid solvent-chain terminator compound of the formula (I) or (II) in the presence of a free radical initiator. The lactam polymer so-obtained may be activated and grafted to (conjugated with) a drug or an enzyme to alter the properties thereof.

REFERENCES:
patent: 2982762 (1961-05-01), Voeks et al.
patent: 3270032 (1966-08-01), Erner
patent: 4057533 (1977-11-01), Hort et al.

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