Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...
Reexamination Certificate
2005-03-22
2005-03-22
Sellers, Robert (Department: 1712)
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
Mixing of two or more solid polymers; mixing of solid...
C424S094100, C424S174100, C424S176100, C424S280100, C514S772700, C525S403000
Reexamination Certificate
active
06870012
ABSTRACT:
A composition exhibiting reverse thermal gellation properties comprises a block polymer having the structure:in-line-formulae description="In-line Formulae" end="lead"?{[An(BCB)An]}min-line-formulae description="In-line Formulae" end="tail"?wherein A is a polyester unit, B is a poly(ethylene oxide) unit, C is a poly(propylene oxide) unit, E is a chain extender unit, n=0-20, and m is greater than 2. The ethylene oxide:propylene oxide ratio ranges from about 0.2:1 to about 40:1. The composition has a final viscosity at a final temperature of more than twice the initial viscosity at an initial temperature wherein the final temperature is at least 10° C. higher than the initial temperature. The composition is combined with either a cellular material for tissue engineering, a cellular material for effecting repair or healing in a patient, or a bioactive agent.
REFERENCES:
patent: 5372723 (1994-12-01), de Geus et al.
patent: 5711958 (1998-01-01), Cohn et al.
Cohn Daniel
Levi Avraham
Coleman Henry D.
Life Medical Sciences, Inc.
Sapone William J.
Sellers Robert
Sudol R. Neil
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