CGRP receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S214020, C514S221000, C540S500000, C540S578000, C540S579000, C540S593000

Reexamination Certificate

active

08039460

ABSTRACT:
Compounds of Formula (I): and Formula (II): (where variables R2, R4, A, B, D, W, X, Y and Z are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

REFERENCES:
patent: 6552043 (2003-04-01), Patchett et al.
patent: WO 00/18764 (2000-04-01), None
patent: WO 03/104236 (2003-12-01), None

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