CGRP receptor antagonists

Details CGRP receptor antagonists CGRP receptor antagonists

2009-03-31

2011-10-25

Kifle, Bruck (Department: 1622)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S303000, C540S500000, C546S118000

Reexamination Certificate

active

08044043

ABSTRACT:
The disclosure generally relates to the novel compounds of formula I, including their salts, which are CGRP receptor antagonists. The disclosure also relates to pharmaceutical compositions and methods for using the compounds in the treatment of CGRP related disorders including migraine and other headaches, neurogenic vasodilation, neurogenic inflammation, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases such as asthma, and chronic obstructive pulmonary disease (COPD).

REFERENCES:
patent: WO 2004/092166 (2004-10-01), None
patent: WO 2004/092168 (2004-10-01), None
patent: WO 2007/120590 (2007-10-01), None

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