CFTR polypeptides, fragments thereof and methods of use to...

Details CFTR polypeptides, fragments thereof and methods of use to... CFTR polypeptides, fragments thereof and methods of use to...

2007-04-17

2007-04-17

Pak, Michael (Department: 1646)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S300000, C530S350000

Reexamination Certificate

active

10030585

ABSTRACT:
The invention relates to biosynthetic maturation of cell surface polypeptides and, more specifically, to particular CFTR polypeptides which exhibit increased transport to the cell surface and tripeptide amino acid sequences that promote or enhance transport of export-incompetent CFTR to the cell surface.

REFERENCES:
patent: 5639661 (1997-06-01), Welsh et al.
patent: 5750571 (1998-05-01), Cheng et al.
patent: 5888722 (1999-03-01), Costa De Beauregard et al.
patent: 5900360 (1999-05-01), Welch et al.
patent: WO 92/05252 (1992-02-01), None
patent: WO 92/05273 (1992-04-01), None
patent: WO 94/12649 (1994-06-01), None
patent: WO 95/25796 (1995-09-01), None
Mickle JE et al. Genotype-phenotype relationships in cystic fibrosis. Med Clin North Am. May 2000;84(3):597-607.
Voet et al. Biochemistry. 1990. John Wiley & Sons, Inc. pp. 126-128 and 228-234.
Yan et al., Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors. Science 290: 523-527, 2000.
Zerangue. et al. A New ER Trafficking Signal Regulates the Subunit Stoichiometry of Plasma Membrane KAIPChannels, Mar. 1999, Neuron, vol. 22, 537-548.

Affiliated with

Also associated with

Rating

CFTR polypeptides, fragments thereof and methods of use to... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with CFTR polypeptides, fragments thereof and methods of use to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and CFTR polypeptides, fragments thereof and methods of use to... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3728035