Certain thiazolo azetidinone compounds

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260239A, 2602391, 260243C, 2602471L, 260250Q, 26029359, 2602948R, 2602948G, 260307A, 260307H, 260308D, 2603322H, C07D20508, C07D49906, C07D50102, C07D21304

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active

039910695

ABSTRACT:
Novel semisynthetic .beta.-lactam intermediates of use in the production of cephalosporins, penicillins and related .beta.-lactam antibiotic compounds are provided. The novel compounds are prepared from .beta.-lactams obtained by cleavage of the 1,2-sulphur-carbon bond of a penicillin 1-oxide (with subsequent internal or external trapping of the sulphur atom to leave a residual substituent as the .beta.-lactam nitrogen) by removal of the said residual substituent by an oxidative cleavage reaction.

REFERENCES:
patent: 3681380 (1972-08-01), Cooper et al.
patent: 3705892 (1972-12-01), Cooper et al.
Cooper et al. III, J. Am. Chem. Soc., vol. 92, pp. 2575-2576 (1970).
Chemical Abstracts Subject Index, vol. 75, p. 3848s (1971).
Barton et al., Chem. Abstracts, vol. 75, Abstract No. 151721k (1971).

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