Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1971-07-30
1976-11-09
Rollins, Alton D.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260239A, 2602391, 260243C, 2602471L, 260250Q, 26029359, 2602948R, 2602948G, 260307A, 260307H, 260308D, 2603322H, C07D20508, C07D49906, C07D50102, C07D21304
Patent
active
039910695
ABSTRACT:
Novel semisynthetic .beta.-lactam intermediates of use in the production of cephalosporins, penicillins and related .beta.-lactam antibiotic compounds are provided. The novel compounds are prepared from .beta.-lactams obtained by cleavage of the 1,2-sulphur-carbon bond of a penicillin 1-oxide (with subsequent internal or external trapping of the sulphur atom to leave a residual substituent as the .beta.-lactam nitrogen) by removal of the said residual substituent by an oxidative cleavage reaction.
REFERENCES:
patent: 3681380 (1972-08-01), Cooper et al.
patent: 3705892 (1972-12-01), Cooper et al.
Cooper et al. III, J. Am. Chem. Soc., vol. 92, pp. 2575-2576 (1970).
Chemical Abstracts Subject Index, vol. 75, p. 3848s (1971).
Barton et al., Chem. Abstracts, vol. 75, Abstract No. 151721k (1971).
Barton Derek Harold Richard
Long Alan Gibson
Looker Brian Edgar
Underwood William George Elphinstone
Wilson Edward McKenzie
Glaxo Laboratories Limited
Rollins Alton D.
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