Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S358000, C424S040000, C424S401000, C424S408000, C424S449000, C424S451000, C424S455000, C424S456000, C424S464000, C424S488000

Reexamination Certificate

active

07825120

ABSTRACT:
Certain substituted ((piperazin-1-ylmethyl)benzyl)urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and may be useful in the treatment of systolic heart failure including congestive heart failure.

REFERENCES:
patent: 3786058 (1974-01-01), Edwards
patent: 3907782 (1975-09-01), Edwards
patent: 3939169 (1976-02-01), Edwards
patent: 4672066 (1987-06-01), Carson et al.
patent: 4787931 (1988-11-01), Henrie, II et al.
patent: 5162360 (1992-11-01), Creswell et al.
patent: 5547966 (1996-08-01), Atwal et al.
patent: 5556969 (1996-09-01), Chambers et al.
patent: 5624937 (1997-04-01), Reel et al.
patent: 5739144 (1998-04-01), Warrellow et al.
patent: 5919811 (1999-07-01), Conti et al.
patent: 5962483 (1999-10-01), Warrellow et al.
patent: 5972975 (1999-10-01), Esser et al.
patent: 5994368 (1999-11-01), Oku et al.
patent: 6001860 (1999-12-01), Hamanaka
patent: 6005008 (1999-12-01), Widdowson et al.
patent: 6174905 (2001-01-01), Suzuki et al.
patent: 6207809 (2001-03-01), Nestler
patent: 6262083 (2001-07-01), Moon et al.
patent: 6329395 (2001-12-01), Dugar et al.
patent: 6407124 (2002-06-01), Rawlins et al.
patent: 6573264 (2003-06-01), Zablocki et al.
patent: 6583282 (2003-06-01), Zhang et al.
patent: 6635641 (2003-10-01), Bender et al.
patent: 6645990 (2003-11-01), Askew et al.
patent: 6656971 (2003-12-01), Wu et al.
patent: 6670376 (2003-12-01), Moran et al.
patent: 6696576 (2004-02-01), Baumann et al.
patent: 6916814 (2005-07-01), Moss et al.
patent: 7176222 (2007-02-01), Morgan et al.
patent: 7371871 (2008-05-01), Schilling et al.
patent: 7399866 (2008-07-01), Morgan et al.
patent: 7491826 (2009-02-01), Morgan et al.
patent: 7507735 (2009-03-01), Morgan et al.
patent: 7538223 (2009-05-01), Morgan et al.
patent: 2002/0165394 (2002-11-01), Dumas et al.
patent: 2003/0045552 (2003-03-01), Robarge et al.
patent: 2003/0096841 (2003-05-01), Robarge et al.
patent: 2003/0207872 (2003-11-01), Riedl et al.
patent: 2003/0229066 (2003-12-01), Hendrix et al.
patent: 2003/0236287 (2003-12-01), Piotrowski et al.
patent: 2004/0019099 (2004-01-01), Aslanian et al.
patent: 2004/0038962 (2004-02-01), Ashworth et al.
patent: 2004/0097483 (2004-05-01), Zeng et al.
patent: 2004/0224875 (2004-11-01), Schilling et al.
patent: 2004/0229937 (2004-11-01), Dumas et al.
patent: 2004/0235829 (2004-11-01), Scott et al.
patent: 2005/0032798 (2005-02-01), Boyer et al.
patent: 2005/0038031 (2005-02-01), Dumas et al.
patent: 2005/0059703 (2005-03-01), Wilhelm et al.
patent: 2005/0159416 (2005-07-01), Morgan et al.
patent: 2006/0014761 (2006-01-01), Morgan et al.
patent: 2006/0025470 (2006-02-01), Morgan et al.
patent: 2006/0241110 (2006-10-01), Morgan et al.
patent: 2007/0066626 (2007-03-01), Morgan et al.
patent: 2007/0161617 (2007-07-01), Morgan et al.
patent: 2007/0197497 (2007-08-01), Morgan et al.
patent: 2007/0197504 (2007-08-01), Morgan et al.
patent: 2007/0197505 (2007-08-01), Morgan et al.
patent: 2007/0197507 (2007-08-01), Morgan et al.
patent: 2007/0208000 (2007-09-01), Morgan et al.
patent: 2009/0036447 (2009-02-01), Morgan et al.
patent: 2009/0099198 (2009-04-01), Morgan et al.
patent: 3147879 (1983-06-01), None
patent: 27965 (1981-05-01), None
patent: 81142 (1983-06-01), None
patent: 0656350 (1995-06-01), None
patent: 921682 (1963-03-01), None
patent: 10-168079 (1998-06-01), None
patent: 11-302173 (1999-11-01), None
patent: 2000-256194 (2000-09-01), None
patent: 2002-220338 (2002-08-01), None
patent: 240935 (1994-11-01), None
patent: WO 84/03884 (1984-10-01), None
patent: WO 92/10468 (1992-06-01), None
patent: WO 93/14074 (1993-07-01), None
patent: WO 96/10559 (1996-04-01), None
patent: WO 98/35941 (1998-08-01), None
patent: WO 98/41510 (1998-09-01), None
patent: WO 98/50346 (1998-11-01), None
patent: WO 98/52558 (1998-11-01), None
patent: WO 98/52559 (1998-11-01), None
patent: WO 99/32106 (1999-07-01), None
patent: WO 99/32111 (1999-07-01), None
patent: WO 99/32436 (1999-07-01), None
patent: WO 99/32463 (1999-07-01), None
patent: WO 99/64394 (1999-12-01), None
patent: WO 00/41698 (2000-07-01), None
patent: WO 01/07411 (2001-02-01), None
patent: WO 01/25190 (2001-04-01), None
patent: WO 01/53274 (2001-07-01), None
patent: WO 02/00626 (2002-01-01), None
patent: WO 02/00632 (2002-01-01), None
patent: WO 02/06246 (2002-01-01), None
patent: WO 02/14311 (2002-02-01), None
patent: WO 02/059106 (2002-08-01), None
patent: WO 02/062763 (2002-08-01), None
patent: WO 02/064576 (2002-08-01), None
patent: WO 02/070462 (2002-09-01), None
patent: WO 02/085857 (2002-10-01), None
patent: WO 02/092576 (2002-11-01), None
patent: WO 03/007942 (2003-01-01), None
patent: WO 03/013523 (2003-02-01), None
patent: WO 03/022820 (2003-03-01), None
patent: WO 03/024933 (2003-03-01), None
patent: WO 03/042164 (2003-05-01), None
patent: WO 03/059258 (2003-07-01), None
patent: WO 03/062224 (2003-07-01), None
patent: WO 03/062235 (2003-07-01), None
patent: WO 03/072098 (2003-09-01), None
patent: WO 03/074501 (2003-09-01), None
patent: WO 03/082278 (2003-10-01), None
patent: WO 03/082808 (2003-10-01), None
patent: WO 03/082861 (2003-10-01), None
patent: WO 03/088967 (2003-10-01), None
patent: WO 03/091229 (2003-11-01), None
patent: WO 03/093250 (2003-11-01), None
patent: WO 03/097576 (2003-11-01), None
patent: WO 2004/000831 (2003-12-01), None
patent: WO 2004/002481 (2004-01-01), None
patent: WO 2004/013102 (2004-02-01), None
patent: WO 2004/013132 (2004-02-01), None
patent: WO 2004/019958 (2004-03-01), None
patent: WO 2004/024729 (2004-03-01), None
patent: WO2004022561 (2004-03-01), None
patent: WO 2004/039306 (2004-05-01), None
patent: WO 2004/101529 (2004-11-01), None
patent: WO 2007/070626 (2007-06-01), None
Tanaka et al. Journal of Medicinal Chemistry, 1998, 41, 2390-2410.
Patani et al. Chemical Reviews, 1996, 41(8), 3147-76.
Trivedi et al. Journal of Medicinal Chemistry, 1994, 37(11), 1652-1659.
International Search Report and Written Opinion mailed Jan. 14, 2005, for Application No. PCT/US04/01069, filed Jan. 14, 2004.
International Search Report and Written Opinion for International Application No. PCT/US05/21100, mailed Aug. 2, 2006, 10 pages.
Office Action mailed Jun. 22, 2006, for U.S. Appl. No. 11/032,227, filed Jan. 11, 2005.
Notice of Allowance and Notice of Allowability mailed Oct. 18, 2006, for U.S. Appl. No. 11/032,227, filed Jan. 11, 2005.
Office Action mailed May 29, 2007, for U.S. Appl. No. 10/890,829, filed Jul. 14, 2004.
Jeffcoat et al., STN Accession Number: 1977:462295; Document No. 87:62295 (1977).
Kempter et al., STN Accession Number: 1984:510849; Document No. 101:110849 (1983).
El-Sharief et al., STN Accession Number: 1987:549199; Document No. 107:14919 (1987).
Office Action mailed Sep. 13, 2007, for U.S. Appl. No. 10/890,829, filed Jul. 14, 2004.
Office Action mailed Sep. 7, 2007, for U.S. Appl. No. 10/541,596, filed Apr. 25, 2006.
Notice of Allowance and Notice of Allowability mailed Jan. 15, 2008, for U.S. Appl. No. 10/890,829, filed Jul. 14, 2004.
Notice of Allowance mailed Dec. 21, 2007, for U.S. Appl. No. 10/541,596, filed Apr. 25, 2006.
Supplementary Partial European Search Report completed Aug. 13, 2007 for European Application No. 04702228.
Office Action mailed Mar. 20, 2008 for U.S. Appl. No. 11/498,986, filed Aug. 4, 2006.
Examiner Search Strategy and Results mailed Mar. 20, 2008 for U.S. Appl. No. 11/498,986, filed Aug. 4, 2006
Office Action mailed Oct. 12, 2007 for U.S. Appl. No. 11/155,940, filed Jun. 16, 2005.
Jeffcoat et al.,Drug Metabolism and Disposition 5(2):157-166.
Mizukura et al., STN Accession No. 113:106314; Original Reference No. 113:17823a,17826a (1990).
Office Action mailed May 22, 2008, for U.S. Appl. No. 10/890,829, filed Jul. 14, 2004.
Notice of Allowance mailed Aug. 11, 2008 for U.S. Appl. No. 11/155,940, filed Jun. 16, 2005.
Office Action mailed Jul. 10, 2008 for U.S. Appl. No. 11/640,438, filed Dec. 14, 2006.
International Search Report and Written Opinion for International Application No. PCT/US2006/047976 mailed Sep. 23, 2008 (10 pages).
Office Action mailed Aug. 28, 2008 for U.S. Appl. No. 11/498,986, filed Aug. 4, 2006.
In

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4184081

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.