Certain steroid N-bis-(haloethyl)-carbamates

Details Certain steroid N-bis-(haloethyl)-carbamates Certain steroid N-bis-(haloethyl)-carbamates

1976-07-30

1977-05-03

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 100

Patent

active

RE0291994

ABSTRACT:
Antitumor active mono and poly N-Bis-(B-haloethyl)-carbamic acid esters of certain estrogenic steroid hormones, especially estradiol; such compounds wherein all hydroxyl groups of the steroid molecule are not thus esterified; and organic and inorganic acid esters of such latter compounds.

REFERENCES:
patent: 2885413 (1959-05-01), Hogg et al.
patent: 3081298 (1963-03-01), Wettstein et al.
Acad. Rep. Populare Romine, Studii Cercelari Chim. 11 (3-4), (1963), pp. 433-439.
Acad. Rep. Populare Romine 10 295 (1962).
Loewenthal: Tetrahedron, vol. 6, pp. 269-303 (1959), pp. 299-302 relied on.
Nogrady et al., "Canadian Journal of Chemistry", No. 40 (1962), pp. 2126-2129.

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