Certain pyridyloxy-or-thio-phenyl propenoic acid derivatives

Details Certain pyridyloxy-or-thio-phenyl propenoic acid derivatives Certain pyridyloxy-or-thio-phenyl propenoic acid derivatives

1983-02-24

1985-01-29

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546300, 546302, 514962, C07D21364, C07D21365

Patent

active

044967357

ABSTRACT:
Novel pyridine compounds and the pharmaceutically acceptable salts thereof having a specific inhibitory activity on thromboxane A.sub.2 biosynthesis in mammals useful for prevention and treatment of various disorders caused by thromboxane A.sub.2, for example, thrombosis, cardiac infarction, diabetic vascular complications, asthma, etc. are disclosed.

REFERENCES:
patent: 4216007 (1980-08-01), Nishiyama et al.
Ohno et al., Chemical Abstracts, vol. 99, No. 21, Abst. No. 175,598x, Nov. 21, 1983.
Iizuka et al., Journal of Medicinal Chemistry, vol. 24, (10), pp. 1139-1148, (1981).

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