Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-12-15
2000-07-04
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514411, 548428, 548452, A61K 3140, A61K 31407, C07D48700, C07D48702, C07D48704
Patent
active
060839716
ABSTRACT:
Compounds of the formula ##STR1## wherein R.sup.1 is lower-alkyl, cycloalkyl or phenyl,
REFERENCES:
patent: 5686459 (1997-11-01), Diederich et al.
patent: 5891900 (1999-04-01), Diederich et al.
M. Dixon, "The Determination of Enzyme Inhibitor Constants" J. Biochem, 55:170-171 (1953).
U. Obst et al., "Design of Novel, Nonpeptidic Thrombin Inhibitors and Structure of a Thrombin--Inhibitor Complex," Angew. Chem. Int. Ed. Engl., 34(16):1739-1742 (1995).
Diederich Fran.cedilla.ois
Obst Ulrike
Weber Lutz
Epstein William H.
Hoffmann-La Roche Inc.
Johnston George W.
Parise John P.
Rotman Alan L.
LandOfFree
Certain oxopyrolo-pyrrole derivatives having thrombin inhibiting does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Certain oxopyrolo-pyrrole derivatives having thrombin inhibiting, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Certain oxopyrolo-pyrrole derivatives having thrombin inhibiting will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1486942