Certain optically active substituted .alpha.,.alpha.-dialkyl-pyr

Details Certain optically active substituted .alpha.,.alpha.-dialkyl-pyr Certain optically active substituted .alpha.,.alpha.-dialkyl-pyr

1991-07-15

1992-10-20

Dentz, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548566, C07D20709

Patent

active

051571285

ABSTRACT:
Optically pure isomers of 7-[3-(1,1-dialkylmethyl-1-amino)-1 -pyrrolidinyl[quinolones and naphthyridones as therapeutically active and safe antibacterial agents are described, as well as pharmaceutical compositions thereof, and a method of treating bacterial infections therewith. Also described is a method of manufacture of the quinolones and naphthyridones as well as the starting materials, the optically pure pyrrolidine moieties for attachment at the 7-position.

REFERENCES:
patent: 4665079 (1987-05-01), Culbertson et al .

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