Certain nitrogen heterocyclic isothiocyanate esters

Details Certain nitrogen heterocyclic isothiocyanate esters Certain nitrogen heterocyclic isothiocyanate esters

1976-08-13

1978-05-16

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

2602948E, 2602948H, 2603068A, 2603068D, 2603068R, 260307H, 260308R, C07D23324, C07D21353

Patent

active

040900266

ABSTRACT:
Process for preparing thioureas by treating isothiocyanates with ammonia and alkylamines. A specific product is N-methyl-N'-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]thiourea, useful as a histamine H.sub.2 -antagonist.

REFERENCES:
patent: 2923712 (1960-02-01), Mizzoni
patent: 3028391 (1962-04-01), Rorig
patent: 3736331 (1973-05-01), Black et al.
patent: 3932443 (1976-01-01), White

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