Certain nicotinic acid esters and corresponding nicotinonitriles

Details Certain nicotinic acid esters and corresponding nicotinonitriles Certain nicotinic acid esters and corresponding nicotinonitriles

1981-05-13

1983-07-12

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546318, C07D21355

Patent

active

043932126

ABSTRACT:
Novel substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their pharmaceutically acceptable salts, certain intermediates and their preparation are disclosed. These pyridines have pharmaceutically useful properties such as .beta.-adrenergic blocking activity.

REFERENCES:
patent: 3946009 (1976-03-01), Wasson et al.
patent: 4000282 (1976-12-01), Baldwin
patent: 4053605 (1977-10-01), Baldwin
patent: 4060601 (1977-11-01), Baldwin
patent: 4115575 (1978-09-01), Frei et al.
Clinical Pharmacology and Therapeutics, vol. 10, No. 3, pp. 292-306 (1969).
Baldwin et al., Journal of Organic Chemistry, vol. 43, No. 12, pp. 2529-2535, (1978).
Sperber et al., Journal of the American Chemical Society, vol. 81, pp. 704-709, (1959).

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