Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-09-07
1993-03-02
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546155, 549400, 549 23, 564265, 514432, 514456, 514640, C07D21520, C07D21522, A61K 3147
Patent
active
051909561
ABSTRACT:
Compounds useful as antiviral agents against DNA containing viruses, such as herpes group viruses, are disclosed. The compounds are selected from the group consisting of: ##STR1## and their pharmaceutically acceptable salts and solvates. Pharmaceutical compositions containing compounds represented by Formula 1.00 are disclosed. Also disclosed are methods of treating a viral infection using compounds represented by Formula 1.00
The compounds of Formula 1.00 are also useful as intermediates to compounds of: ##STR2## Compounds of Formula 1.0 are useful as antiviral agents against the same viruses that the compounds of Formula 1.00 are useful against.
REFERENCES:
patent: 3132140 (1964-05-01), Jaffe
patent: 4022770 (1977-05-01), L'Eplattenier et al.
patent: 4959363 (1990-09-01), Wentland
Chemical Abstracts vol. 76(5), Abst. 24862-C. Jan. 31, 1972.
Derwent Abstract J90005-752-B.
Derwent Abstract J89035-827-B.
J. Chem. Soc. 438 (1964).
CA: 97:15948t (1982).
CA: 104124s (1981).
Afonso Adriano
Gentles Margaret J.
Weinstein Jay
Boxer Matthew
Dicker Eric S.
Jeanette Henry C.
Rotman Alan L.
Schering Corporation
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