Certain N-alkyl-2-[(quinolin-3-yl)-tetrahydro-pyran or furan]-2-

Details Certain N-alkyl-2-[(quinolin-3-yl)-tetrahydro-pyran or furan]-2- Certain N-alkyl-2-[(quinolin-3-yl)-tetrahydro-pyran or furan]-2-

1985-08-16

1988-06-14

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546175, 546268, 546283, 546284, 514336, C07D21560, C07D40909, A61K 3147

Patent

active

047512342

ABSTRACT:
Thioformamide derivatives of the formula: ##STR1## wherein R is hydrogen or alkyl (1 to 4 C), Het is pyridin-3-yl[optionally substituted by alkyl (1 to 4 C) or a halogen], quinolin-3-yl, pyridazin-4-yl, pyrimidin-5-yl, thiazol-5-yl, thieno[2,3-b]pyridin-5-yl or thieno[3,2-b]pyridin-6-yl, and Y is a valency bond or a methylene radical, are new compounds, which are particularly useful as antihypertensive agents.

REFERENCES:
patent: 4272534 (1981-06-01), Aloup et al.
patent: 4277484 (1981-07-01), Rosen
patent: 4379154 (1981-05-01), Aloup et al.
patent: 4456758 (1984-06-01), Aloup et al.
patent: 4568682 (1986-02-01), Aloup et al.

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