Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-04-16
1993-03-23
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546285, 546330, 548503, 548505, C07D20914, C07D20918, A61K 31405
Patent
active
051964465
ABSTRACT:
Heteroarylethenediyl compounds wherein the heteroaryl group can be mono- or icyclic heteroaryl and the aryl group can be or mono- or bicyclic carbocyclic, said compound optionally substituted or polysubstituted, with the proviso that the heteroaryl group is not furyl or thienyl when the ethenediyl group has geminal cyano substituents, and pharmaceutical compositions comprising said compounds, and the use thereof for inhibiting a protein tyrosine kinase portion of a receptor selected from epidermal growth factor and platelet derived growth factor in a patient suffering from such disorder.
REFERENCES:
patent: 3149148 (1964-09-01), Kladko
patent: 3157663 (1964-11-01), Bencze et al.
patent: 3196158 (1965-07-01), Bencze et al.
patent: 3337565 (1967-08-01), Bencze et al.
patent: 3337568 (1967-08-01), Bencze et al.
patent: 3527785 (1970-09-01), Ozaki et al.
patent: 4064266 (1977-12-01), Birchall et al.
patent: 4532329 (1985-07-01), Haken et al.
patent: 4539325 (1985-09-01), Heeres
patent: 4600712 (1986-07-01), Haken et al.
patent: 4626543 (1986-12-01), Kollmeyer
patent: 4678793 (1987-07-01), Klaus et al.
patent: 4769384 (1988-09-01), Kise et al.
patent: 4816476 (1989-03-01), Klaus et al.
patent: 4826984 (1989-05-01), Berlin et al.
patent: 4833247 (1989-05-01), Krause
Chemical Abstracts, 107(19):17642h (1987).
Gazit Aviv
Gilon Chaim
Levitzki Alexander
Rotman Alan L.
Yissum Research Development Company of the Hebrew University of
LandOfFree
Certain indole compounds which inhibit EGF receptor tyrosine kin does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Certain indole compounds which inhibit EGF receptor tyrosine kin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Certain indole compounds which inhibit EGF receptor tyrosine kin will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1352026