Certain heterocyclic sulfoximide derivatives

Details Certain heterocyclic sulfoximide derivatives Certain heterocyclic sulfoximide derivatives

1980-05-15

1981-10-13

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2603472, 546261, 546283, 546284, 546293, 549 59, 549 60, 549 65, 424275, 424285, A61K 3144, C07D21362, C07D40712, C07D40912

Patent

active

042948380

ABSTRACT:
Sulphoximide derivatives of the general formula: ##STR1## wherein R.sub.1 is a phenyl, thienyl, furyl or pyridyl ring; R.sub.2 is a thienyl, furyl, or pyridyl ring; R.sub.3 and R.sub.4 are the same or are different and are alkyl groups containing up to 6 carbon atoms or together with the nitrogen atom to which they are attached form a pyrrolidine, piperidine, or morpholine ring; and n is a whole number from 1 to 5; and the pharmaceutically acceptable organic and inorganic acid addition and quaternary ammoniuim salts thereof. The compounds of the invention exhibit anti-bronchospasmolytic activity.

REFERENCES:
patent: 3637664 (1972-01-01), Saltzinger et al.
Index Nominum, pp. 118, 122, 150, 177, 195, 199, 220, 225, 277, 331, 588, 683, 733, 736, 739 and 839, Zurich (1979).
Chem. Abstracts, vol. 72, No. 9, item No. 43,151d, Mar. 1970 abstracting British Patent No. 1,168,700, dated 29 Oct. 1969 (9 pages).
Burger, Medicinal Chemistry, Second Edition, p. 497, Interscience Pub. (1960).

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