Certain glycine derivatives as factor Xa inhibitors for use...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C546S186000, C546S187000, C546S188000

Reexamination Certificate

active

11456589

ABSTRACT:
Compounds of formula (I)in which R, R1, R2, n and X1have the meanings given in the specification are Factor Xa inhibitors useful in the treatment of thrombotic disorders.

REFERENCES:
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patent: 6521609 (2003-02-01), Doods et al.
patent: 6855715 (2005-02-01), Liebeschuetz et al.
patent: 6900196 (2005-05-01), Liebeschuetz et al.
patent: 2004/0254374 (2004-12-01), Jones et al.
patent: 2005/0026928 (2005-02-01), Wiley et al.
patent: WO 99/11657 (1999-03-01), None
patent: WO 99/11658 (1999-03-01), None
patent: WO 00/71493 (2000-11-01), None
patent: WO 00/76971 (2000-12-01), None
patent: WO 01/96323 (2001-12-01), None
Jones, Stuart D, et al., Bioorganic & Medicinal Chemistry Letters 11 (2001) 733-736.

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