Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a new c

Details Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a new c Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a new c

1991-11-27

1993-06-01

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544251, C07D47114

Patent

active

052161595

ABSTRACT:
The invention encompasses a compound of the formula ##STR1## and the pharmaceutically acceptable non-toxic salts thereof wherein X, W, Y, R, and R2 are variables.
These compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs thereof and are useful in the diagnosis and treatment of anxiety, sleep, and seizure disorders, overdose with benzodiazepine type drugs, and enhancement of alertness.

REFERENCES:
L. Eric Crane et al; J. Org. Chem. 1980, 45, 3827-3831.

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