Certain cycloalka-(b)-pyrazolo(3,4-d)-pyridin-3-one derivatives

Details Certain cycloalka-(b)-pyrazolo(3,4-d)-pyridin-3-one derivatives Certain cycloalka-(b)-pyrazolo(3,4-d)-pyridin-3-one derivatives

1987-11-19

1989-05-02

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514269, 514272, 514273, 514275, 514278, 514287, 514300, 544320, 544321, 544322, 544331, 546 82, 546118, 546 15, 546 64, A61K 3144, C07D47104

Patent

active

048268542

ABSTRACT:
Certain 8 to 12 membered cycloalka-[b]-pyrazolo[3,4,-d]-pyridin-3- one compounds which are useful as benzodiazepine receptor modulators are disclosed.

REFERENCES:
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patent: 4524146 (1985-01-01), Yokoyama
patent: 4602014 (1986-07-01), Yokoyama
patent: 4647566 (1987-03-01), Yokoyama
patent: 4740512 (1988-04-01), Yokoyama
Pharmacologist 28,112 (1986).
Bennett et al, "CGS 17867A: A non-Sedating Benzodiazephine Agonist" Aug. 18, 1986.
Drug Senelopment Research 6:313-325 (1985).
J. Med. Chem. 25, 337-339 (1982) Yokoyama et al.
J. Chem. Soc. Perkin I, 857 (1978) Kumar et al.

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