Certain bicycloalkane and azabicycloalkane-1,1-diphosphonic acid

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514102, 546 21, 546 23, 558161, 562 21, C07F 938, C07F 940, C07F 958, A61K 31675

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active

051048639

ABSTRACT:
This invention relates to pyrindine-diphosphonic acid derivatives which are useful in treating or preventing diseases characterized by abnormal calcium and phosphate matabolism, in particular those which are characterized by abnormal bone metabolism. This invention further relates to pharmaceutical compositions which contain the novel compounds of the present invention, and to a method of treating or preventing diseases characterized by abnormal calcium and phosphate metabolism utilizing a compound of the present invention.

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patent: 4330537 (1980-10-01), Francis
Mustafa et al., Justus Liebigs Ann. Chem., 698, 109 (1966) (Chem. Abs. 66:75881).
Gross et al., Justus Liebigs Ann. Chem., 707, 35 (1967) (Chem. Abs. 67:108709).

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