Certain benzazocinone and benzazoninone derivatives

Details Certain benzazocinone and benzazoninone derivatives Certain benzazocinone and benzazoninone derivatives

1984-02-09

1985-08-27

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

2602393B, 2602393T, A61K 31395, C07D22506

Patent

active

045378851

ABSTRACT:
Variously substituted 1-carboxymethyl-3-(carboxymethylamino)-benzazocin-2-one and benzazonin-2-one derivatives are disclosed as angiotensin converting enzyme inhibitors and anti-hypertensive agents. Synthesis of, pharmaceutical compositions and methods of treatment utilizing such compounds are included.

REFERENCES:
patent: 3661927 (1972-05-01), Zivkovic
patent: 3748321 (1973-07-01), Krapcho
patent: 4322439 (1982-03-01), Klemm et al.
patent: 4410520 (1983-10-01), Watthey
patent: 4470988 (1984-09-01), Watthey
patent: 4473575 (1984-09-01), Watthey
Saito, I. J. Am. Chem. Society, 101, 7332, (1979).

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