Certain aryl and cycloalkyl fused imidazopyrazinediones; a new c

Details Certain aryl and cycloalkyl fused imidazopyrazinediones; a new c Certain aryl and cycloalkyl fused imidazopyrazinediones; a new c

1995-06-06

1998-11-24

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D49120, C07D47114, C07D48704, A61K 31495

Patent

active

058408886

ABSTRACT:
##STR1## The present invention encompasses compounds of formula (I), and the pharmaceutical acceptable non-toxic salts thereof wherein: where X represents hydrogen or lower alkyl; W represents an aryl group unsubstituted or substituted with various organic and inorganic substituents; (a) represents (b); (c); (d) or (e) or (a) represents (f), where A, B, C, D, and E represent carbon or nitrogen substituted with hydrogen or various organic and inorganic substituents; and n is 0, 1, or 2; Y, R.sub.3, R.sub.4, R.sub.12, and R.sub.13 are various organic and inorganic substituents. These compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs thereof and are useful in the diagnosis and treatment of anxiety, sleep, and seizure disorders, overdose with benzodiazepine drugs, and enhancement of memory.

REFERENCES:
patent: 5130430 (1992-07-01), Shaw
Occelli et al Il Farmaco 39, 322 (1984).

Affiliated with

Also associated with

Rating

Certain aryl and cycloalkyl fused imidazopyrazinediones; a new c does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Certain aryl and cycloalkyl fused imidazopyrazinediones; a new c, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Certain aryl and cycloalkyl fused imidazopyrazinediones; a new c will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1703741