Certain 6,7-dihydro-3(2-nitrophenyl)-1,2-benzisoxazol-4(5H)-ones

Details Certain 6,7-dihydro-3(2-nitrophenyl)-1,2-benzisoxazol-4(5H)-ones Certain 6,7-dihydro-3(2-nitrophenyl)-1,2-benzisoxazol-4(5H)-ones

1995-05-31

1996-03-26

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 14, 546103, C07D26120, C07D21910

Patent

active

055022030

ABSTRACT:
Novel 9-aminotetrahydroacridines and related compounds, intermediates and processes for the preparation thereof, and a method of relieving memory dysfunction are disclosed.

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patent: 5441727 (1995-08-01), Chatterjee et al.
Chemical Abstracts, vol. 117, (No. 7) Abst. No. 69,882-r, Aug. 17, 1992.
A. A. Akhrem, et al., Synthesis, p. 43 (Jan., 1987) entitled "A Convenient One-Step Synthesis of Tetrahydrobenzisoxazoles via 1,3-Cycloaddition of Nitrile Oxides to Cyclohexane-1,3-dione Derivatives" and published in Russia.
G. M. Shutske, Journal of Heterocyclic Chemistry, vol. 27, pp. 1617 to 1621 (Sep., 1990) entitled "A Novel Synthesis of the Isoxazole 5,4,3-k!acridine Ring System" and published in the United States.
G. M. Shutske, et al., Journal of Medicinal Chemistry, vol. 32, pp. 1805 to 1813 (Aug., 1989) entitled "9-Amino-1,2,3,4-tetrahydroacridine-1-ols: Synthesis and Evaluation as Potential Alzheimers's Disease Therapeutics" and published in the United States.

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