Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1985-01-08
1987-03-17
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 85, 514 89, 514 90, 514 92, 546 22, 546 23, 544157, 544232, 544141, 544144, 548112, 548413, 548415, A61K 3150, A61K 31535, A61K 3144, A61K 31425
Patent
active
046507914
ABSTRACT:
A novel phospholipid of the formula: ##STR1## wherein R.sup.1 is an alkyl group of 10 to 24 carbon atoms, R.sup.2 is a cyclic imide group and A.sup.+ is a cyclic ammonio group and a salt thereof have platelet activating factor inhibiting activity and are useful for prevention and treatment of circulatory disorders and allergic bronchial asthma.
REFERENCES:
patent: 4408052 (1983-10-01), Hozumi et al.
patent: 4426525 (1984-01-01), Hozumi et al.
patent: 4542219 (1985-09-01), Hozumi et al.
patent: 4551532 (1985-11-01), Hozumi et al.
patent: 4565865 (1986-01-01), Hozumi et al.
Life Sciences, 32, 1975 (1983).
J. Org. Chem., 48, 1197 (1983).
Central Patents Index, Basic Abstracts Journal, Sec. B:FARMDOC 33708 K/14 B03 TAKE 25.08.81, J58035-116.
Biochemical and Biophysical Research Communications, 122, 824-830 (1984).
Nishikawa Kohei
Nomura Hiroaki
Tsushima Susumu
Rotman Alan L.
Takedo Chemical Industries, Ltd.
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