Certain 3,4-dihydro-2H-pyrano[2,3-b]pyridines

Details Certain 3,4-dihydro-2H-pyrano[2,3-b]pyridines Certain 3,4-dihydro-2H-pyrano[2,3-b]pyridines

1992-10-14

1994-08-09

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 14, 546 15, 546303, C07D491052, C07D49104

Patent

active

053367715

ABSTRACT:
The present invention relates to processes and intermediates for the preparation of spiro-heteroazolones. The latter compounds are useful as aldose reductase inhibitors.

REFERENCES:
patent: 4980357 (1990-12-01), Goldstein et al.
March, Advanced Organic Chemistry, Second Edition, pp. 98-113, McGraw-Hill Publishes, 1979.
Chemical Abstracts, vol. 67, No. 15, Oct. 9, 1967, Columbus, Ohio, USA, H. Sliwa: "Synthesis of New Heterocylic Compounds", p. 6926; ref. No. 73537Y & C. R. Acad. Sci., Paris, Ser. C 264 [23], 1893-5, [1967], abstract.
Chemical Abstracts, vol. 113, No. 3, Jul. 16, 1990. R. Sarges et al.: "Spiro Hydantoin Aldoso Reductase Inhibitors Derived from 8-aza-4-chromanones", p. 648; ref. No. 23773V & J. Med., 1990, 33[7], 1859-65 (abstract).

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