Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1982-12-08
1985-06-18
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514269, 514274, 514293, 544310, 544316, 544317, 544319, 544320, 544321, 544328, 544331, 546 82, A61K 31505, C07D40114
Patent
active
045241465
ABSTRACT:
Pyrazolo[4,3-c]quinolin-3-ones of the formula ##STR1## e.g. wherein R.sub.1 is an aromatic heterocyclic radical selected from quinolyl, isoquinolyl, pyrimidyl and thiazolyl, or such said heterocyclic radical mono- or di-substituted by lower alkyl, lower alkoxy or halogen; R.sub.2 and R.sub.3, each independently, represents hydrogen or lower alkyl; R.sub.4 and R.sub.5, each independently, represents hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; and pharmaceutically acceptable salts thereof, are benzodiazepine receptor modulators.
REFERENCES:
patent: 4312870 (1982-01-01), Yokoyama
Lal, et al., "Indian Jour. Chem.", vol. 15B, 1977, pp. 359-363.
Life Sciences 30, 363, 2245, 1982.
J. Med. Chem. 25, 337, 1982.
European Patent Application 22,078 published 1/7/81, Abstract only enclosed.
Scrip No. 731, Sep. 27, 1982, p. 15.
Ciba-Geigy Corporation
Gruenfeld Norbert
Hollrah Glennon H.
Turnipseed James H.
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